Scott J. Hultgren, Ph.D.
Helen L. Stover Professor of Molecular Microbiology
Director, Center for Women's Infectious Disease Research
|Mailing Address||Campus Box 8230
660 S. Euclid Ave.
St. Louis, MO 63110
|Office Location||Room 10102
McDonnell Pediatric Research Building
|Office Phone:||(314) 362-6772|
|Lab Phone:||(314) 362-7042|
Category(ies) of Research:
Descriptor of Research:
We are interested in the mechanisms involved in the increased prevalence of urinary tract infection (UTI) in diabetics. To address this issue, we have developed a diabetic mouse model of UTI and are comparing differences in UTI pathogenesis between diabetic and non-diabetic mice in various genetic backgrounds. We have found, in collaboration with Dr. Joel Schilling, an increase in UPEC colonization and resulting inflammation in the kidneys in a pre-diabetic model.